• Excellence

  • Tenacious

  • Relentless

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PIPELINE

Metabolic Disease

Program
Indication
Target Gene
Delivery
Discovery
Lead Optimization
IND Enabling
Clinical Stage

Genetic Disease

Program
Indication
Target Gene
Delivery
Discovery
Lead Optimization
IND Enabling
Clinical Stage

Infectious Disease

Program
Indication
Target Gene
Delivery
Discovery
Lead Optimization
IND Enabling
Clinical Stage

Metabolic Disease

Program

YOLT-101

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  • Indication

    Familial Hypercholesterolemia (FH)

  • Target Gene

    PCSK9

  • Delivery

    In vivo   LNP

Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-102

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  • Indication

    ASCVD

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-103

  • Indication

    Undisclosed

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Genetic Disease

Program

YOLT-201
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  • Indication

    Transthyretin Amyloidosis (ATTR)

  • Target Gene

    TTR

  • Delivery

    In vivo  LNP

Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-202
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  • Indication

    Alpha-1 Antitrypsin Deficiency (AATD)

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-203
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  • Indication

    Primary Hyperoxaluria (PH1)

  • Target Gene

    HAO1

  • Delivery

    In vivo  LNP

Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-204
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  • Indication

    Undisclosed

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-205
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  • Indication

    HAE

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Infectious Disease

Program

YOLT-301
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  • Indication

    Hepatitis B

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-302
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  • Indication

    Undisclosed

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

Discovery
Lead Optimization
IND Enabling
Clinical Stage
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