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ABOUT YolTech

ABOUT YolTech

YolTech Therapeutics is a clinical-stage in vivo gene editing company committed to pioneering the next generation of precision genetic medicines. Our approach combines innovative gene editing technologies with an advanced lipid nanoparticle (LNP) delivery system, creating a versatile platform designed to address a wide range of serious diseases. Central to our mission is the development of internal capabilities, including end-to-end manufacturing, to ensure the highest standards of quality and scalability. Our lead candidate, targeting ATTR, marks a significant milestone as China's first LNP-mediated in vivo gene editing therapy to enter clinical development. With promising early clinical outcomes, YolTech is also advancing therapies for familial hypercholesterolemia (FH) and primary hyperoxaluria type 1 (PH1). As a company dedicated to transforming the treatment landscape, YolTech continues to push the boundaries of what is possible in gene editing.

  • 37M
    +

    USD Raised

  • 80
    +

    Patents Filed

  • 3
    +

    Programs in Clinical Development

DEVELOPMENT

  • 2024
    • April

      First Patient Dosed in Clinical Trial of YOLT-101

    • June

      Phase I Clinical Trial of YOLT-201

    • August

      First Patient Dosed in Clinical Trial of YOLT-203

    • September

      FDA RPDD for YOLT-203

  • 2024
    • Jan

      New Members to SAB Appointed

    • Feb

      Base Editor Patent Granted

    • Mar

      YOLT-201 IND Application Approved

    • Apr

      CRISPR/Cas Patent Granted

  • 2023
    • Mar

      GMP Manufacture Site Established

    • Jun

      Novel Lipid Patent Granted

    • Jun

      YOLT-201 GLP Tox Study Completed

      Pre-IND submitted

    • Nov

      Series A+ Financing

    • Dec

      IND for leading Asset

      Estimated to have IIT data and IND filing

  • 2022
    • Feb

      Shanghai R&D Center Established

    • Apr

      Novel Base Editor Patent Filed

    • Jun

      Series A Financing

    • Jul

      Novel CRISPR/Cas Patent Filed

    • Aug

      Preclinical POC in NHP

      Durable PCSK9 reduction in NHPs after single dose i.v.

  • 2021
    • Jul

      Company Establishment

    • Sep

      Angel Round Financing

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    2024
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    2024
  • b1_img2023.jpg
    2023
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    2022
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    2021